Free Newsletters - Space News - Defense Alert - Environment Report - Energy Monitor
. Earth Science News .




EPIDEMICS
AIDS scientists optimistic of AIDS cure, for some
by Staff Writers
Paris (AFP) May 22, 2013


Top AIDS scientists were optimistic Wednesday of finding a cure for the disease that has claimed 30 million lives -- but said it might not work for all people.

The experts have high hopes for a treatment that will be given at an early stage of infection -- most likely a cocktail that includes an immunity booster and a virus killer.

But they said people with a long-running, untreated infection and a compromised immune system may never benefit from an envisioned "functional cure" -- which means a person retains traces of the virus but no symptoms.

"We have had some very interesting little lights at the end of the tunnel in individual studies," Anthony Fauci, director of the US National Institute of Allergy and Infectious Diseases, said on the sidelines of a Paris conference to mark the 30th anniversary of the discovery of HIV, the virus that causes AIDS.

"It is a difficult road, but a feasible road," he said.

Proof of vaccine feasibility lay with a Thai study dubbed RV144, which in 2009 demonstrated protection for 31 percent of some 16,000 people given an experimental vaccine, said Fauci.

"I think we will likely have a (vaccine that works at) better than 31 percent, but there's certainly the possibility that we won't have a 90 percent," Fauci told reporters.

"And I think there is even a greater possibility that we won't have a pristine cure that would essentially cure everybody who is HIV infected.

"I think it's not only possible that that won't happen -- I think it is likely that that won't happen."

Fauci and other scientists point to the difficulties they have encountered to completely expunge the virus that destroys the immune system and exposes infected people to pneumonia, TB, and other opportunistic disease.

Antiretroviral drugs slow down virus reproduction, allowing people to live symptom-free lives and slowing transmission to others, but much of the virus hides away in "reservoir" cells only to reemerge and start spreading again once treatment stops.

A team of scientists at Monash University in Melbourne, Australia, is experimenting with an anti-cancer drug to flush the virus out of its hiding place, then to be killed.

"Ultimately, we want a cure that is available to a large number of people," a member of the team, Sharon Lewin from Monash University, told AFP at the conference.

"I think the virus is persistent in people for multiple reasons, not one reason... now we are looking at the virus that hides in the DNA, we are finding the way to take on part of the problem. Ultimately we will need a combined approach, like we had for cancer."

Two other, smaller studies using antiretrovirals at a very early stage of infection, before viral levels build up, have excited hopes of a cure.

One involved a baby in the US state of Mississippi apparently cleared of the virus after being given aggressive antiretroviral treatment within 30 hours of birth.

The other is a small French study of 14 HIV patients, known as the VISCONTI cohort, who started on drugs within 10 weeks of infection and were able to stop the daily treatment after three years, staying healthy.

For Francoise Barre-Sinoussi, a 2008 Nobel co-recipient for the HIV discovery, a functional cure is the most likely option -- with patients in permanent remission after stopping treatment.

"The international scientific community agrees that it will likely not be a single drug, but a combination of molecules and drugs with a vaccine that will allow this remission," she said.

An estimated 34 million people are infected with HIV worldwide, and about 1.8 million die every year.

Fauci would not be drawn on the timing for a vaccine for people most at risk, saying only: "It's not going to be 30 years, but it's not going to be a year."

.


Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola






Comment on this article via your Facebook, Yahoo, AOL, Hotmail login.

Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle




Memory Foam Mattress Review
Newsletters :: SpaceDaily :: SpaceWar :: TerraDaily :: Energy Daily
XML Feeds :: Space News :: Earth News :: War News :: Solar Energy News





EPIDEMICS
Concept flu vaccine may protect against many strains
Paris (AFP) May 22, 2013
Scientists unveiled a concept vaccine against flu Wednesday they said may protect against various strains with a single jab. Tested in ferrets, considered good human models, the synthetic vaccine uses nanotechnology to attack parts of the influenza virus that different strains have in common, they wrote in the journal Nature. "It provides a basis for development of universal influenza va ... read more


EPIDEMICS
How should geophysics contribute to disaster planning

Rescuers dig for life after US tornado kills 24

Huge China sinkhole kills five: authorities

How should geophysics contribute to disaster planning?

EPIDEMICS
3-D modeling technology offers groundbreaking solution for engineers

NASA Seeks High-Performance Spaceflight Computing Capabilities

SPUTNIX is granted a license for space activity

Stanford Engineers' New Metamaterial Doubles Up on Invisibility

EPIDEMICS
Scientists explore roots of future tropical rainfall

World's smallest droplets

Shifts in global water systems markers of The Anthropocene epoch

New Stanford Nanoscavengers Could Usher In Next Generation Water Purification

EPIDEMICS
Sea level influenced tropical climate during the last ice age

World's biggest ice sheets likely more stable than previously believed

Tropical air circulation drives fall warming on Antarctic Peninsula

Research into carbon storage in Arctic tundra reveals unexpected insight into ecosystem resiliency

EPIDEMICS
Hong Kong hails the return of the duck

Argentine beef trade decimated by policy shifts

Keeping fruit, vegetables and cut flowers fresh longer

Danone strikes deals to meet Chinese taste for yogurt

EPIDEMICS
6.0 quake off Russia's far-east Kamchatka coastline

Penn Research Helps Paint Finer Picture of Massive 1700 Earthquake

Five hurt as quake hits Algeria: medics

TD Alvin Marks Starts Of US Hurricane Season

EPIDEMICS
Chinese vice premier on business visit to Zimbabwe

Madagascar security forces summon political rivals

African Sahel reels from ever more frequent crises: UN

SLeone, China sign huge infrastructure deal

EPIDEMICS
Climate change boosted human development: study

Do salamanders hold the solution to regeneration

Brain frontal lobes not sole centre of human intelligence

Searching for Clandestine Graves with Geophysical Tools




The content herein, unless otherwise known to be public domain, are Copyright 1995-2014 - Space Media Network. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement