Earth Science News  





. Compound May Prevent Neuron-Degeneration


Nagoya, Japan (UPI) Sep 14, 2005
Scientists from Japan's Nagoya University School of Medicine say they've found a chemical compound that prevents a neuron-degeneration process.

The researchers, writing in the journal Nature Medicine, said the compound known as 17-AAG might be used as a molecular targeted drug, the Asahi Shimbun reported Tuesday.

"The concept of molecular targeted drugs is an important one for developing new drug therapies for neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease," said Gen Sobue, who led the research team.

Neuron degeneration is linked to the accumulation of mutant proteins in nerve cells and experiments have confirmed 17-AAG has a special effect on such proteins, the newspaper reported.

The researchers said the compound lies dormant when there is nothing unusual about a certain part of the protein receptor. But when abnormalities develop the compound functions to inhibit and degrade the suspect protein, Asahi Shimbun said.

Molecular targeted drugs are a focus of research in cancer prevention, and 17-AAG has been considered a possible chemical compound for use in such drugs.

Related Links
SpaceDaily
Search SpaceDaily
Subscribe To SpaceDaily Express

Croatia Zoo Opens Cages For World's Most Dangerous Species - Humans
Zagreb (AFP) Sep 13, 2005
Visitors to Zagreb zoo can now experience what it feels like to be a caged animal, zoo management announced Tuesday.

.
Get Our Free Newsletters Via Email
  



  • Powerful Eye-In-The-Sky Gives Rescuers The Optical Imagery They Need To Save Lives
  • Bush Takes Blame For Katrina Response
  • Anger Grows Among Those Ignored In Katrina's Wake
  • Space-Borne Rainfall Monitoring Could Save Lives, Mitigate Dangers

  • Climate Change Will Affect Carbon Sequestration In Oceans, Model Shows
  • Lethal Needle Blight Epidemic May Be Related To Climate Change
  • Lethal Needle Blight Epidemic May Be Related To Climate Change
  • Meteor Dust Could Affect Climate, Study Suggests

  • Tropical Deforestation Affects Rainfall In U.S. And Around Globe
  • NASA Satellite Data Used By INPE Provides Rapid Analysis Of Amazon
  • Cryosat: The Ice Edge Holds The Key
  • Appreciating The CryoSat Challenge - Guy Ratier, Project Manager

  • Oil Prices Jump After US Inventories Data
  • Portugal To Build World's Largest Solar Power Station
  • India-EU To Work Together on ITER
  • Oil Prices Steady Amid Cooler Energy Demand

  • Harmless Virus May Help Fight Bird Flu
  • Drug Resistant Bird Flu In Southeast Asia
  • Ebola Menaces Great Ape Populations Of Central Africa
  • Unusual Antibiotics Show Promise Against Deadly Superbugs

  • New Tiger Cubs In Myanmar Zoo, Breast-Feeding Woman On Standby
  • Trap-Breaking Chimpanzees Found In Guinea
  • Guerrillas Threaten Gorillas In Volatile Eastern DR Congo
  • Building Life From Star-Stuff

  • Canada To Press Chinese President Over Pollution
  • Sickness Spreads Among Hurricane Holdouts
  • Katrina Disease Kills Five
  • Prosecutors Reject Newmont's Arguments In Indonesia Pollution Trial

  • Compound May Prevent Neuron-Degeneration
  • Croatia Zoo Opens Cages For World's Most Dangerous Species - Humans
  • Parts Of Brain Battle Over Decisions
  • New Techniques Study The Brain's Chemistry, Neuron By Neuron

  • The content herein, unless otherwise known to be public domain, are Copyright 1995-2006 - SpaceDaily.AFP and UPI Wire Stories are copyright Agence France-Presse and United Press International. ESA PortalReports are copyright European Space Agency. All NASA sourced material is public domain. Additionalcopyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by SpaceDaily on any Web page published or hosted by SpaceDaily. Privacy Statement