Free Newsletters - Space - Defense - Environment - Energy - Solar - Nuclear
..
. Earth Science News .




EPIDEMICS
Scientists say vaccine temporarily brakes HIV
by Staff Writers
Madrid (AFP) Jan 03, 2013


A team of Spanish researchers say they have developed a therapeutic vaccine that can temporarily brake growth of the HIV virus in infected patients.

The vaccine, based on immune cells exposed to HIV that had been inactivated with heat, was tested on a group of 36 people carrying the virus and the results were the best yet recorded for such a treatment, the team said.

"What we did was give instructions to the immune system so it could learn to destroy the virus, which it does not do naturally," said Felipe Garcia, one of the scientists in the team at Barcelona University's Hospital Clinic.

The therapeutic vaccine, a shot that treats an existing disease rather than preventing it, was safe and led to a dramatic drop in the amount of HIV virus detected in some patients, said the study, published Wednesday in Science Translation Medicine.

After 12 weeks of the trial, the HIV viral load dropped by more than 90 percent among 12 of the 22 patients who received the vaccine. Only one among the 11 patients who received a control injection without the vaccine experienced a similar result.

After 24 weeks, the effectiveness had begun to decline, however, with seven of the 20 remaining patients receiving the vaccine enjoying a similar 90-percent slump in viral load. No-one in the control group of 10 patients experienced such a decline in the virus.

The vaccine lost its effectiveness after a year, when the patients had to return to their regular combination therapy of anti-retroviral drugs.

Researchers said the results were similar to those achieved with a single anti-retroviral drug, used to block the growth of HIV.

"It is the most solid demonstration in the scientific literature that a therapeutic vaccine is possible," they said in a statement.

The vaccine allowed patients temporarily to live without taking multiple medicines on a daily basis, which created hardship for patients, could have toxic side-effects over the long term and had a high financial price, the team said.

"This investigation opens the path to additional studies with the final goal of achieving a functional cure -- the control of HIV replication for long periods or an entire life without anti-retroviral treatment," the researchers said in a statement.

"Although we still have not got a functional cure, the results published today open the possibility of achieving an optimal therapeutic vaccine, or a combination of strategies that includes a therapeutic vaccine, and could help to reach that goal," they said.

The team said it took seven years to get to this point, and the researchers would now work on improving the vaccine and combining it with other therapeutic vaccines over the next three or four years.

According to latest UN figures, the number of people infected by HIV worldwide rose to 34 million in 2011 from 33.5 million in 2010.

.


Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola






Comment on this article via your Facebook, Yahoo, AOL, Hotmail login.

Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle




Memory Foam Mattress Review
Newsletters :: SpaceDaily :: SpaceWar :: TerraDaily :: Energy Daily
XML Feeds :: Space News :: Earth News :: War News :: Solar Energy News





EPIDEMICS
Penn Team Mimicking a Natural Defense Against Malaria to Develop New Treatments
Philadelphia PA (SPX) Jan 01, 2013
One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it. Researchers from the Perelman School of Medicine at the University of Pennsylvania, working with collaborators from Drexel University, The Children's Hospital of Philadelphia, and Johns Hopkins University, have identified a protein in human blood plat ... read more


EPIDEMICS
Fukushima 'unprecedented challenge': new Japan PM

Natural catastrophes caused $160 bn in damage: Munich Re

Congress approves $9.7 bn aid for storm Sandy victims

Republican leader vows to hold vote on stalled storm aid

EPIDEMICS
COM DEV wins commercial contract from MacDonald Dettwiler and Associates

Thai 'scavengers club' turns trash to treasure

Malaysia convoy in Australia rare earth plant protest

All Systems Go for Highest Altitude Supercomputer

EPIDEMICS
US town bans bottled water

Jellyfish suggest blooms are a consequence of periodic global fluctuations

Outrage over Hong Kong's 'shark fin rooftop'

Estonia's lake-maker lives his dream

EPIDEMICS
CryoSat hits land

Study shows rapid warming on the West Antarctic Ice Sheet

Antarctic science drill project called off

W. Antarctic warming among world's fastest

EPIDEMICS
Brazil mulls retaliation for ban on beef

Chinese trigger Australian baby milk run

Poland bans cultivation of GM maize, potatoes

Even in same vineyard, different microbes may create variations in wine grapes

EPIDEMICS
Floods hit southeast Niger

Sodden Britain marks second wettest year in 2012

Hundreds homeless, 2 dead, after heavy rains in Rio

Effort on to save China relics from flood

EPIDEMICS
Poachers kill four rhinos in Zimbabwe

Seven killed as Nigerian soldiers clash with Islamists

Angola detains nine exiled DR Congo officers over 'plot'

China firm to acquire major African iron ore mine: Xinhua

EPIDEMICS
Study refutes accepted model of memory formation

Fluctuating environment may have driven human evolution

Decision to give a group effort in the brain

Scientists construct first map of how the brain organizes everything we see




The content herein, unless otherwise known to be public domain, are Copyright 1995-2014 - Space Media Network. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement