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. Dyslexia in Chinese, English speakers is different: study

by Staff Writers
Chicago (AFP) April 7, 2008
Chinese- and English-speaking dyslexics have different neurological deficits, according to a study released Monday which suggests that dyslexia may be different brain disorders in the two cultures.

English speakers with the reading disability typically have functional abnormalities in posterior parts of the brain associated with reading and possibly less gray matter in these areas also.

In Chinese dyslexics, on the other hand, the functional and structural brain abnormalities related to reading correspond with the left middle frontal region of the brain, according to new research.

The new research is based on brain scans performed on 16 dyslexic Chinese speakers and 16 of their peers with normal reading ability during the course of a couple of tests.

Researchers first asked the 32 Beijing primary school students to look at two Chinese characters in different size font to see if they could identify the difference in size.

Having used this question to establish which part of their brains was involved with reading, the investigators then presented the students with two more Chinese characters and asked them if the two characters rhymed.

The second question was designed to test the students' phonological awareness, their sensitivity to the sound structure of language, which is considered an important and reliable predictor of reading ability.

The scans revealed that the students with the reading disability had less activity in the left middle frontal gyrus on the second task than the children without the disability.

They also had less gray matter in this brain region than the children with normal reading skills.

Further, the Chinese dyslexic children did not have any abnormalities in the parts of the brain that have been shown to be problematic in alphabetic-language dyslexics.

While surprising, the contrast can be explained by the fact that the Chinese language uses characters, while English uses a letter alphabet, one of the researchers said.

"At the functional level, it's easy to understand why Chinese and English speakers use different parts of the brain to read language," said Li-Hai Tan, a professor of linguistics and neuroscience at the University of Hong Kong, and author on the paper.

"The different brain networks accommodate the different features of English and Chinese. The two systems are dramatically different. Chinese is pictographic and English is more phonological, or sound-based."

However, he said that it was striking that the Chinese dyslexic children had less gray matter in the middle frontal gyrus, and that was probably a function of genetics, since this phenomenon is thought to be largely genetic.

This would suggest that the genetic makeup of Chinese speaking dyslexics is different from that of English speakers with the same disorder since they have reductions of gray matter in different sites of the brain.

The study involved researchers from the University of Hong Kong, the Beijing Institute of Technology, and the University of Pittsburgh and appears in the Proceedings of the National Academy of Sciences.

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Scientists Reshape Y Chromosome Haplogroup Tree Gaining New Insights Into Human Ancestry
Cold Spring Harbor NY (SPX) Apr 04, 2008
The Y chromosome retains a remarkable record of human ancestry, since it is passed directly from father to son. In an article published in Genome Research, scientists have utilized recently described genetic variations on the part of the Y chromosome that does not undergo recombination to significantly update and refine the Y chromosome haplogroup tree.

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