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Some swine flu victims contagious 8 days or more: studies

by Staff Writers
San Francisco (AFP) Sept 15, 2009
Some swine flu victims remain contagious more than eight days after their symptoms have vanished, much longer than expected, said two studies presented at a meeting of experts.

Currently, US health authorities recommend that people who contract the A(H1N1) virus wait 24 hours after the fever has subsided before returning to their normal activities to avoid any risk of spreading the disease.

However the two studies -- one conducted in Canada and the other in Singapore -- concluded that between 19 and 30 percent of people infected with swine flu may remain contagious for eight days or more after their fever has vanished.

In the Canadian study, eight patients from a group of 43 swine flu patients -- or 19 percent of the group -- still had a live virus that was able to multiply, making them contagious eight days after their fever had abated, said Gaston De Serres, a specialist at the National Public Health Institute of Quebec.

However none of the patients showed any trace of the virus 10 days after fever broke, De Serres said.

"This study shows you're not contagious for a day or two. You're probably contagious for about a week" after the fever has abated, De Serres told reporters at the American Society for Microbiology's 49th annual conference on antimicrobial agents and chemotherapy meeting this week.

A second study conducted by David Lye of the Tan Tock Seng Hospital in Singapore found that 20 to 30 percent of a group of 70 swine flu patients still carried the live virus -- and were potentially infectious -- eight days after fever ended, and a few still remained contagious up to 16 days later.

However the infectious period was shorter for patients treated with antiviral medicine.

De Serres said that the Canadian study did not look at the density of the viral load at the eight-day mark, but that tests were continuing. This information is key in estimating the true risk of contagion.

"The current recommendation suggests that fever subsides in three to four days, and people go work by fifth day," said Daniel Jernigan, deputy director of the influenza division at the US Centers for Disease Control and Prevention.

"Some people will continue to shed live virus after their fever stops, we know that," he said, adding that current recommendations "are intended to decrease infection, not completely eliminate infection.

"If we had a virus with a very high attack rate or death rate we might have a very different policy," he said.

While noting that both studies were carried out on small sample groups, Frank Lowy, a virologist at Columbia University in New York, told reporters that if confirmed in new studies, the results could be significant in efforts to contain the swine flu spread.

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GSK says one-dose swine flu vaccine effective
London (AFP) Sept 14, 2009
British drugs giant GlaxoSmithKline said on Monday that trials had shown one dose of its swine flu vaccine produced "a strong immune response". "The results demonstrate that after one dose the candidate vaccine can provide a strong immune response," GSK said in a statement. The trial, which is taking place in Germany, involves 130 healthy volunteers aged 18 to 60. Chinese biotech ... read more

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