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FLORA AND FAUNA
All that pecking may give woodpeckers brain damage
by Brooks Hays
Washington (UPI) Feb 2, 2018

Feeding chicken necks to dogs may cause paralyzing condition
Washington (UPI) Feb 2, 2018 - Scientists have linked a sometimes-deadly dog paralysis condition with the consumption of raw chicken -- specifically, chicken necks.

The latest study, published this week in the Journal of Veterinary Internal Medicine, found eating raw chicken increased some dog's risk of developing acute polyradiculoneuritis, APN, by nearly 7,000 percent.

"It is a rare but very debilitating condition where the dog's hind legs first become weak and then may progress to affect the front legs, neck, head and face," Dr. Matthias le Chevoir, a researcher at the University of Melbourne's U-Vet Werribee Animal Hospital, said in a news release. "Some dogs may die from the disease if their chest becomes paralyzed."

"Most dogs eventually recover without treatment but it may take up to six months or more in some cases," le Chevoir said. "It can be difficult for owners to nurse their pet until the condition gradually improves."

APN is similar to Guillain-Barré syndrome, or GBS, which similarly weakens muscles to the point of near-paralysis in humans. In both cases, the immune system becomes overreactive and unregulated. As the condition worsens, the system attacks the body's nerve roots, causing paralysis.

Researchers have previously linked GBS in humans to the invasion of a type of bacteria called Campylobacter. Because the bacteria is found in raw chicken, researchers hypothesized that the consumption of raw poultry could explain APN in dogs.

Scientists studied several dozen dogs with and without APN, documenting differences in their physical condition and interviewing owners to establish different behavior patterns. Scientists found dogs showing symptoms of APN were 9.4 times more likely be infected with Campylobacter.

"The microbe Campylobacter is likely to be the reason for the dysregulation of the dog's immunity and therefore, the symptoms of paralysis," Dr. Loreno Martinez-Anton said.

The link between raw chicken consumption and APN was strongest among small dogs. Scientists believe the correlation can be explained by the consumption of chicken necks.

"Smaller dogs are more likely to be fed smaller bones like chicken necks," Martinez-Anton said.

The message for dog owners is simple, researchers said: until more about APN is understood, stop feeding dogs raw chicken.

"We would recommend that owners choose regular dog food rather than chicken necks until we know more about this debilitating condition," researchers wrote.

Turns out, woodpeckers do get brain damage. All that pecking comes at a price, new research shows -- or does it?

Until now, many assumed woodpeckers had a remarkably resilient brain. Woodpeckers absorb 1,200 to 1,400 g's of force every time they slam their head and beak into a tree. Just 60 to 100 g's is enough to cause a concussion in humans.

"There have been all kinds of safety and technological advances in sports equipment based on the anatomic adaptations and biophysics of the woodpecker assuming they don't get brain injury from pecking," Peter Cummings, researcher at the Boston University School of Medicine, said in a news release. "The weird thing is, nobody's ever looked at a woodpecker brain to see if there is any damage."

When scientists analyzed the brains of woodpeckers from collections at Chicago's Field Museum and the Harvard Museum of Natural History, they discovered elevated levels of tau, a protein linked with degenerative brain disease in humans.

In moderation, tau proteins support healthy brain function.

"The basic cells of the brain are neurons, which are the cell bodies, and axons, which are like telephone lines that communicate between the neurons," said researcher George Farah. "The tau protein wraps around the telephone lines -- it gives them protection and stability while still letting them remain flexible."

But brain damage can cause tau to accumulate and begin sabotaging brain function instead of supporting it.

"Cognitive, emotional, and motor function can be compromised," said Cummings.

Just as has been found in the brains of athletes who sustain multiple brain injuries during their careers, woodpecker brains featured larger amounts of tau than the brains of similarly sized, non-pecking peers.

Scientists can't be certain that the woodpeckers suffer brain injuries, but the evidence suggests they do.

"The earliest woodpeckers date back 25 million years -- these birds have been around for a long time," Cummings said. "If pecking was going to cause brain injury, why would you still see this behavior? Why would evolutionary adaptations stop at the brain? There's possibility that the tau in woodpeckers is a protective adaptation and maybe not pathological at all."

If tau is indeed a protective agent, the new research -- published this week in the journal PLOS One -- could inspire new ways of thinking about brain injuries and how to prevent them.

"Is there something we can pick out to help humans with neurodegenerative diseases?" Cummings said. "The door's wide open to find out what's going on and how we can apply this to humans."


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FLORA AND FAUNA
Lab-on-a-chip for tracking single bacterial cells
Basel, Switzerland (SPX) Feb 01, 2018
Researchers at the Biozentrum of the University of Basel, together with researchers from the Max Planck Institute in Dresden, have set up a novel lab-on-a-chip with accompanying automatic analysis software. As they report in Nature Communications, this integrated setup can be used to study gene regulation in single bacterial cells in response to dynamically controlled environmental changes. It is hardly bigger than a matchbox and yet there is a laboratory en miniature on this chip. Single bacteria ... read more

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